Quetiapine Oral Route Correct Use The situations Seroquel XR is accredited to treat vary from these of Seroquel. Vraylar and Seroquel are comparable medication, however they have some differences. Both are atypical (second-generation) antipsychotic medication, which means they work to enhance your temper, thinking, and conduct. Vraylar and Rexulti are both atypical (second-generation) antipsychotics,...